A simple comparison to how the LS motors respond better to mods than the 6.1 are the following:
Long tube headers on my buddies 2005 LS2 Vette added a good 20 rwhp throughout the rpm range to his car, still on stock heads and cam. Long tube headers on my Magnum with a cam did not add more than 5 or 10 rwhp at most. Same buddy now has a ported intake, headers with h/f cats, catback, ported TB, t-stat, and tune and is making 410rwhp and 400 rwtq. No other work done.
You can go pretty aggressive on an LS2/LS3 cam on stock heads (in the high 220 and 230 int/exh duration range) with only changing the pushrods, retainers and springs. You cannot do that on a stock 6.1 head because of the PTV clearance. Case in point, I had a buddy of mine with a 6.0 GTO that had stock heads and our mods being essentially the same (cam only, headers with h/f cats, CAI, pulley, t-stat, ported intake, ported TB) and his car pulled close to 450 rwhp and 415 rwtq with HP tuners. His cam was in the 230 int/exh duration range and he was still using the stock 2.5" exhaust with Flowmasters welded in. I don't know of many, if any, cam only (suppoting mods above) SRT8 cars making that kind of power. Plus his car pulls to 6500 rpm.
Pretty good proof to me.